If you use Sonicare AirFloss with water, periodically filling the reservoir with a small amount of mouthrinse and pressing the activation button repeatedly until there is no spray left will help prevent bacteria growth.
If you use Sonicare AirFloss with mouthrinse on a daily basis, periodically rinsing the unit with water and allowing it to dry will help to keep the unit from developing a build-up of stickiness or chemicals from the mouthrinse.
For more in-depth cleaning, you can easily clean the reservoir as desired using a small cotton swab. Be careful not to leave any particles within the reservoir.
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